Clinical research · Orlando, Florida
Shaping the future of healthcare through life‑changing clinical trials.
For more than 25 years, Orlando Immunology Center has helped develop every antiretroviral used to treat HIV today — and contributed to the cure for Hepatitis C.

Participation benefits
Being part of a study should never be a burden.
For eligible participants, clinical trial participation may include:
- Study medications provided at no cost
- Study-related labs provided at no cost
- Study-related visits provided at no cost
- Monitoring by study-related providers
- Transportation assistance, when needed, through Lyft, Uber, or bus passes
- Stipend provided at each study visit
Our legacy
A legacy of innovation that makes OIC a trusted leader in clinical research.
OIC investigators have participated in the development of every commercially available HIV antiretroviral, played an important role in the cure for Hepatitis C, and partnered with the NIH on COVID-19 vaccines and treatments. When you join a study at OIC, you become part of that history.
Research conducted with
- Gilead
- Merck
- ViiV · GSK
- Janssen
- AbbVie
- NIH · NIAID
- Roche
- TaiMed
Looking for clinical care instead?
Orlando Immunology Center is dedicated exclusively to clinical research. For primary care, sexual health and HIV medicine, visit OIC Inspired — our allied clinic, an independent practice founded by the same physicians.
Research team
Investigators who wrote the literature
Edwin DeJesus, MD, FACP, FIDSA
Medical Director · Principal Investigator
Federico Hinestrosa, MD, FACP
Associate Medical Director
Latest news
From the research desk

New once-monthly PrEP study now enrolling
OIC begins enrollment for a Phase 3 trial of a monthly oral tablet for HIV prevention.

Drs. Rolle and Hinestrosa featured on Spectrum News 13
Our investigators discussed the future of long-acting HIV prevention in Central Florida.

OIC presents at CROI 2026
New data from our once-weekly oral treatment studies presented at the year’s leading HIV conference.
Clinical Research